"Dutasteride yog ib qho tshuaj uas thaiv cov enzyme hu ua 5-alpha reductase (5-AR)," piav qhia Dr. Simon Pimstone, tus tsim, thiab tus thawj coj, ntawm XYON Health Inc. "Cov enzyme no yog lub luag haujlwm rau kev tsim cov dihydrotestosterone (lossis DHT), uas yog androgen hormone uas ua lub luag haujlwm tseem ceeb hauv kev loj hlob ntawm prostate thiab txiv neej qauv plaub hau poob.
Dutasteride feem ntau siv nyob rau hauv cov xwm txheej uas cov plaub hau poob yog qhov dav lossis tsis teb rau lwm txoj kev kho mob hu ua finasteride.
Ob qho kev kho mob no thaiv 5-AR, txawm li cas los xij, Pimstone taw qhia tias dutasteride inhibits ob hom enzyme hu ua isoforms I thiab II, thaum finasteride tsuas yog ua rau isoform II.
Finasteride tseem tsuas thaiv txog 70% ntawm kev hloov pauv ntawm testosterone rau hauv DHT. Dutasteride tuaj yeem thaiv ntau dua 90% Trusted Source.
Noj dutasteride qhov ncauj ua haujlwm los ntawm kev txwv tsis pub hloov pauv ntawm testosterone rau DHT hauv lub cev kom DHT tsis muaj sijhawm mus txog cov hauv paus plaub hau.
Thaum siv tshuaj pleev ib ce, nws ua haujlwm los ntawm kev tso tseg DHT hloov dua siab tshiab hauv cov hauv paus plaub hau.
