Kev tshawb fawb qhia tau hais tias IGF-1 tej zaum yuav yog ib qho tseem ceeb nyob rau hauv ib tug xov tooj ntawm neurological mob, xws li autism. Qhov tseeb, cov menyuam yaus uas muaj kev puas siab puas ntsws qhia qis dua lub hlwb ntawm IGF-1 dua li kev tswj hwm hnub nyoog, tawm tswv yim tias qis IGF-1 concentrations hauv lub hlwb, tshwj xeeb tshaj yog thaum muaj hnub nyoog ntxov, yuav cuam tshuam kev loj hlob thiab tseem ceeb. nyob rau hauv lub pathogenesis ntawm autism.
Kev tshawb fawb hauv nas qauv ntawm autism qhia tias IGF-II thiab cov analogues zoo li IGF-1 DES thim rov qab txhua qhov kev tsis txaus ntseeg cuam tshuam nrog cov xwm txheej. Cov nas tswj hwm IGF-II tsuas yog tsib hnub tau pom tias muaj kev sib raug zoo ntawm kev sib raug zoo, kev paub txog cov khoom tshiab zoo dua, txhim kho cov ntsiab lus ntawm kev ntshai, txo qis kev rov ua dua / kev coj cwj pwm, kev tu kom zoo, thiab ntau dua. Cov nas txawm pom tias txhim kho kev nco.
Cov kev tshawb pom no yuav tsum tsis txhob muaj qhov xav tsis thoob vim kev tshawb fawb qhia tias kev puas hlwb yuav tshwm sim los ntawm kev cuam tshuam hauv kev txhim kho synapse thiab zoo ib yam li pathologically, rau lwm yam mob neurodevelopmental xws li fragile X syndrome, tuberous sclerosis, thiab Angelman syndrome. IGF-1 thiab nws cov analogues, uas muaj txiaj ntsig zoo ntawm cov synapses, yog li cov neeg sib tw zoo tshaj plaws rau kev tshawb nrhiav ntau yam kev kho mob hauv cov teeb meem no.
