Testosterone thiab testosterone undecanoate yog ob qho tib si ntawm cov txiv neej pw ua ke hormone testosterone, tab sis lawv txawv nyob rau hauv ob peb txoj kev tseem ceeb, nrog rau lawv cov qauv tshuaj, lawv yuav siv li cas, thiab lawv cov kev kho mob siv:
Chemical Structure:
Testosterone: Testosterone yog lub ntuj thiab thawj txiv neej cov tshuaj hormones. Nws yog tsim nyob rau hauv cov qe ntshav (hauv txiv neej) thiab, nyob rau hauv ib tug tsawg npaum li cas, nyob rau hauv lub zes qe menyuam (nyob rau hauv cov poj niam) thiab cov qog adrenal nyob rau hauv ob qho tib si poj niam txiv neej.
Testosterone Undecanoate: Testosterone undecanoate yog ib hom hluavtaws ntawm testosterone uas muaj ester, tshwj xeeb tshaj yog undecanoate ester, txuas rau nws. Qhov no ester prolongs cov tshuaj hormones tso tawm thiab txo qhov zaus ntawm kev tswj hwm.
Kev tswj hwm:
Testosterone: Testosterone muaj nyob rau hauv ntau hom, nrog rau kev txhaj tshuaj, transdermal thaj ua rau thaj, gels, cream, thiab lub qhov ncauj capsules. Daim ntawv tshwj xeeb thiab txoj hauv kev ntawm kev tswj hwm yog nyob ntawm tus mob uas tau kho thiab tus neeg mob yam tseem ceeb.
Testosterone Undecanoate: Testosterone undecanoate feem ntau yog siv los ntawm kev txhaj tshuaj intramuscular lossis ua tshuaj ntsiav hauv qhov ncauj. Daim ntawv qhov ncauj feem ntau yog siv los kho cov tshuaj hormone hloov.
Pharmacokinetics:
Testosterone: Nyob ntawm daim ntawv, testosterone muaj ntau yam pharmacokinetics. Piv txwv li, kev txhaj tshuaj testosterone feem ntau yuav tsum tau txhaj tshuaj tsawg dua piv rau cov ntawv hauv qhov ncauj vim lawv cov esterification.
Testosterone Undecanoate: Testosterone undecanoate, nrog rau undecanoate ester, muaj lub sijhawm ntev ntawm kev txiav txim siab piv rau lwm hom testosterone. Qhov no tso cai rau kev tswj hwm tsawg dua.
Kev siv tshuaj kho mob:
Testosterone: Testosterone yog siv rau ntau lub hom phiaj kho mob, xws li tshuaj hormone hloov kho rau cov tib neeg uas tsis tshua muaj testosterone ntau ntau, feem ntau yog vim muaj mob xws li hypogonadism. Nws kuj yog siv los kho ncua kev puberty thiab qee hom mob qog noj ntshav hauv cov poj niam.
Testosterone Undecanoate: Testosterone undecanoate feem ntau yog siv los kho cov tshuaj hormone hloov, tshwj xeeb tshaj yog rau cov tib neeg uas tsis tshua muaj testosterone qib. Qhov ncauj formulation ntawm testosterone undecanoate, hu ua Andriol lossis Restandol, tau pom zoo rau kev siv kho mob hauv qee lub tebchaws.
Hauv cov ntsiab lus, ob qho tib si testosterone thiab testosterone undecanoate yog cov ntaub ntawv ntawm tib cov tshuaj hormones, tab sis testosterone undecanoate tau raug hloov kho nrog ester kom ntev nws tso tawm hauv lub cev. Qhov kev xaiv ntawm ob yog nyob ntawm tus mob uas tau kho, txoj kev nyiam ntawm kev tswj hwm, thiab lwm yam ntawm tus kheej. Kev siv tshuaj kho mob ntawm cov tshuaj no yuav tsum tau saib xyuas los ntawm tus kws kho mob.