Hauv cov txiv neej androgens kho qhov kev loj hlob thiab kev loj hlob ntawm cov txiv neej hauv nruab nrog cev thiab kev loj hlob thiab kev saib xyuas ntawm cov yam ntxwv ntawm kev sib deev theem nrab. Androgens kuj feem ntau nce protein anabolism thiab txo cov protein catabolism. Exogenous kev tswj hwm ntawm androgens ua rau ua kom cov tswv yim tswv yim ua rau txo qis endogenous testosterone ntau lawm.
Methyltestosterone yog ib qho hluavtaws androgen receptor agonist. Methyltestosterone yog ib qho testosterone mimic siv los kho cov txiv neej uas tsis muaj testosterone. Tsis tas li ntawd nws yog siv nyob rau hauv kev kho mob cancer ntawm lub mis nyob rau hauv postmenopausal cov poj niam raws li ib tug antineoplastic neeg sawv cev. Methyltestosterone yog Testosterone derivative bearing ib pawg methyl ntawm 17 alpha txoj hauj lwm uas ua rau kom muaj bioavailability. Methyltestosterone khi cytosolic androgen receptors thiab ligand-receptor complex functions raws li ib tug transcription yam regulating qhia ntawm androgen teb cov noob. Androgen teb cov noob yog lub luag haujlwm rau kev loj hlob thiab kev loj hlob ntawm cov txiv neej pw hauv nruab nrog cev thiab lwm yam kev sib deev yam ntxwv. Cov tshuaj anabolic xws li methyltestosterone txhawb nqa anabolism thiab inhibit catabolism thiab yog li txhawb kev loj hlob ntawm cov leeg nqaij, lub zog thiab lub zog.
Methyltestosterone yog ib qho ntawm ntau cov tshuaj kho androgen hluavtaws. Kev siv tag nrho ntawm exogenous androgens xws li methyltestosterone raug txwv thiab ua tib zoo saib xyuas raws li cov kev mob tshwm sim tsis zoo xws li kev loj hlob ntawm prostate tuaj yeem tshwm sim. Tsis ntev los no cov non-steroidal androgen receptor modulators tau tsim los uas tuaj yeem ua rau androgen receptor tab sis tsis txo qis rau dihydrotestosterone lossis aromatized rau estradiol thiab yog li tsis pom qhov tsis zoo ntawm lub hom phiaj.
