Viagra (sildenafil citrate) txhim kho penile erections nyob rau hauv cov txiv neej nrog erectile kawg (ED) los ntawm kev xaiv inhibiting cGMP- tshwj xeeb phosphodiesterase type 5 (PDE5), uas muaj nyob rau hauv tag nrho cov hlab ntsha.https://www.giantrawsource.com/raw-steroid-powder/raws-powder-viagra-sildenafil-citrate.htmlNws kuj tseem ua rau muaj kev cuam tshuam me me tiv thaiv PDE6, uas yog tam sim no tshwj xeeb hauv pas nrig thiab lub khob cij photoreceptors. Thaum noj ntau dua, sildenafil ua rau pom cov tsos mob me me thiab tsis pom kev hauv cov neeg mob tsawg (feem ntau yog xiav tinge rau qhov muag, nce qhov ci ntawm lub teeb). Yog li ntawd, cov teebmeem ntawm sildenafil ntawm lub qhov muag pom tau raug tshawb xyuas nyob rau hauv ntau yam kev tshawb fawb soj ntsuam thiab preclinical. Hauv kev tshawb fawb preclinical, sildenafil qhia tau hais tias cov teebmeem hloov pauv hloov pauv ntawm hluav taws xob teb rau lub teeb. Nyob rau hauv ntev - cov kev tshawb fawb toxicology nyob rau hauv uas cov tsiaj tau raug ntau ntau ntawm cov tshuaj kho neeg mob siab tshaj plaws, cov kev ntsuam xyuas ntxaws tau qhia tias tsis muaj kev cuam tshuam rau cov qauv lossis kev ua haujlwm ntawm lub qhov muag. Cov teebmeem ntawm sildenafil tau raug tshawb xyuas hauv cov kev tshawb fawb pom kev hauv cov neeg tuaj yeem pab dawb thiab hauv cov neeg mob qhov muag; sildenafil tsis cuam tshuam rau qhov pom kev pom, pom kev pom, thiab qhov sib txawv rhiab heev. Qhov tseeb tsuas yog qhov tshwm sim tsis ntev los no, qhov tsis zoo me me ntawm kev ntxub ntxaug xim tshwm sim nyob ib puag ncig lub sijhawm ntawm cov qib ntshav plasma. Hauv kev tshawb fawb ntev -lub sij hawm ntev, tsis muaj kev cuam tshuam ntev ntawm sildenafil ntawm qhov muag pom. Tom qab kev lag luam, sildenafil tau muab tshuaj rau ntau tshaj 15 lab tus txiv neej nrog ED. Cov piv txwv cais ntawm ntau yam kev pom tsis zoo tshwm sim tau raug tshaj tawm. Tsis muaj tus qauv zoo ib yam tau tshwm sim los qhia txog qhov ntev - lub sij hawm cuam tshuam ntawm sildenafil ntawm retina lossis lwm yam qauv ntawm lub qhov muag. Raws li qhov kev paub dhau los no, tsis sib xws, luv luv -lub sijhawm, ib feem inhibition ntawm PDE5 lossis PDE6 los ntawm sildenafil tsis zoo li yuav ua rau muaj kev hloov pauv ntev ntev.
