Tuam Tshoj GHRP-2 5mg/vial Peptides Siab Zoo

Kev piav qhia

Kev loj hlob hormone-tso peptide-2 (GHRP-2) yog ib qho ntawm ntau cov tshuaj hluavtaws met-enkephalin uas suav nrog D-amino acids tsis zoo. Lawv tau tsim los rau lawv txoj kev loj hlob hormone (GH) tso tawm cov haujlwm, tom qab ntawd hu ua GH secretatogues. Lawv tsis muaj kev ua haujlwm opioid tab sis yog cov muaj zog stimulators ntawm GH tso tawm. Cov secretatogues no txawv ntawm qhov kev loj hlob hormone tso tawm cov tshuaj hormones (GHRH los yog GHRF) nyob rau hauv uas lawv sib koom tsis muaj kev sib raug zoo thiab muab lawv cov kev ua haujlwm los ntawm kev ua ntawm ib tug txawv kiag li receptor, ghrelin receptor.

GHRP-2, tshuaj ntsuam xyuas, yog ib tus tswv cuab muaj zog tshaj plaws ntawm GHRP tsev neeg. Nws tau pom tias muaj txiaj ntsig zoo rau cov neeg laus ntawm qhov ncauj thiab intranasal nrog rau txoj kev iv ntawm kev tswj hwm.

GHRP-2 thawj zaug ua tus Growth Hormone (GH) nce tus neeg sawv cev. Muaj rau 6 amino acids, peptide ua haujlwm los ntawm kev tsim cov khoom tsim GH nrog rau kev tsim khoom thiab tso tawm ghrelin. Kev tso tawm ntawm ghrelin yog qhov tseem ceeb vim nws kuj pab txhawb GH tso tawm hauv lub cev. Nrog GHRP-2, qhov no ua tiav los ntawm peptide suppressing somatostatin, ib yam tshuaj uas txwv kev tso tawm GH hauv lub cev.

Raws li ghrelin tso tawm, lub cev tshaib plab. GHRP-6 paub zoo tias ua rau muaj kev tshaib plab heev, uas tej zaum yuav tsis muaj teeb meem nyob ntawm tus neeg xav tau lossis lub hom phiaj. GHRP-2 yuav tso tib lub ghrelin hauv lub cev, tab sis yuav tsum tsis txhob ua li ntawd hauv txoj kev uas txhawb nqa qhov kev tshaib kev nqhis tseem ceeb. Qee qhov nce hauv qab los noj mov yog qhov tsis tuaj yeem zam tau, tab sis GHRP-2 zoo li yuav muaj kev cuam tshuam tsawg dua rau kev qab los noj mov dua li GHRP-6. Nyob rau hauv luv luv, GHRP-2 pab nyob rau hauv kev txhawb nqa ntawm natural GH ntau lawm nyob rau hauv lub cev, uas yog nqa nrog nws heev heev kev ua tau zoo raws li zoo raws li kev noj qab haus huv cov kev pab cuam rau cov neeg siv.

GHRP -2 Peptide ua haujlwm li cas?

Nws tuaj yeem txhawb kev loj hlob hormone (GH) ntau lawm los ntawm kev ua haujlwm ntawm pituitary hlwb.

Nws tuaj yeem yog qhov muaj peev xwm GRF (kev loj hlob hormone tso tawm) receptor ligand.

Nws tuaj yeem qhib cov calcium channel thiab nce calcium secretion thiab GH ntau lawm hauv cov lus teb rau calcium overload.

Nws tuaj yeem ua rau GH tso tawm los ntawm kev ua kom txoj hauv kev cAMP thiab protein kinase C.

Kev tshawb fawb qhia tias kev ua haujlwm adenylate cyclase tuaj yeem nce ntxiv thaum GHRP-2 raug tswj hwm hauv cov chaw sim tswj. Cov kev tshawb fawb kwv yees tias cov protein kinase tuaj yeem qhib tau, thiab cAMP yuav raug tsim. Kev nce calcium ntau ntxiv thiab kev loj hlob hormone tso tawm tuaj yeem tshwm sim los ntawm cov qib cAMP thiab cov protein kinase, raws li tau hais los ntawm cov kev tshawb fawb no.

Cov Khoom Ua Tau Ntawm GHRP-2

Cov kws tshawb fawb qhia tias lub peev xwm ntawm GHRP-2 yuav zoo ib yam li lwm cov peptides uas tuaj yeem txhawb kev loj hlob hormone ntau lawm. Qee cov khoom ntawm GHRP-2 peptide, raws li kev kwv yees los ntawm kev sim tshuaj, tuaj yeem yog:

● Muaj peev xwm nce qib ntawm kev loj hlob hormone

● Muaj peev xwm nce cov nqaij ntshiv

● Muaj peev xwm ua kom yoog tau

● Muaj peev xwm txhim kho kev sib koom tes

● Muaj peev xwm pw tsaug zog

● Muaj peev xwm tiv thaiv kev laus

● Muaj peev xwm txhim kho lub cev muaj peev xwm thiab lub zog

Cov kws tshawb fawb kwv yees tias qhov nce hauv cov tshuaj hormones loj hlob thiab kev loj hlob zoo li insulin zoo li -1 (IGF-1) yuav yog qhov kawg ntawm GHRP-2 kev nthuav qhia. Raws li tau hais los saum no, cov khoom ntawm peptide tsis txwv rau cov uas twb tau hais lawm; cov kev tshawb fawb qhia tias nce qib ntawm IGF-1 kuj tseem tuaj yeem ua kom cov nqaij mos txhim kho thiab txo cov rog hauv lub cev.

Dosage Of GHRP-2

Qhov ntau npaum li cas ntawm Kev Loj Hlob Hormone-Releasing Peptide-2 (GHRP-2) tuaj yeem sib txawv nyob ntawm tus kheej yam, suav nrog hnub nyoog, qhov hnyav, lub hom phiaj qoj ib ce, thiab rhiab rau peptide.

Yog tias koj tab tom xav txog kev siv GHRP-2, nws yog ib qho tseem ceeb uas yuav tsum tau ceev faj thiab sab laj nrog tus kws kho mob uas paub txog cov tshuaj no. Lawv tuaj yeem muab kev taw qhia tus kheej raws li koj cov kev xav tau tshwj xeeb thiab cov hom phiaj.

Qhov ntawd tau hais tias, thaum tib neeg siv GHRP-2, cov koob tshuaj feem ntau yog ntsuas hauv micrograms (mcg) thiab tau muab los ntawm subcutaneous (hauv qab daim tawv nqaij) lossis txhaj tshuaj intramuscular. Nov yog cov lus qhia dav dav rau kev noj GHRP-2:

Kev pib noj: Ib qho pib ntau npaum li cas rau GHRP-2 tej zaum yuav nyob hauv thaj tsam ntawm 100-200 mcg rau ib qho tshuaj.

Zaus: GHRP-2 feem ntau xav tau ntau qhov kev txhaj tshuaj txhua hnub vim nws lub neej luv luv. Cov neeg siv tuaj yeem tswj hwm nws ib zaug lossis ob zaug ib hnub.

Maj mam nce: Nws raug nquahu kom pib nrog qhov tsawg npaum li cas thiab maj mam nce nws lub sijhawm, yog tias xav tau, thaum saib xyuas koj cov lus teb thiab cov kev mob tshwm sim.

Abstract

GHRP {{0}} yog ib tug hluavtaws agonist ntawm ghrelin, lub plab peptide uas tau tshawb pom tshiab uas khi rau txoj kev loj hlob hormone (GH) secretagogue receptor. Ghrelin muaj ob qho kev cuam tshuam loj, txhawb nqa GH secretion thiab qab los noj mov / noj mov. GHRP-2 tau raug tshawb fawb ntau rau nws cov txiaj ntsig raws li kev loj hlob hormone secretagogue (GHS). Cov kev tshawb fawb tsiaj tau pom tias nws cuam tshuam rau kev noj zaub mov. Txawm li cas los xij, txawm tias GHRP-2 tuaj yeem txhawb kev qab los noj mov hauv tib neeg thaum tswj hwm tsis tau paub. Peb subcutaneously infused 7 lean, cov txiv neej noj qab haus huv nrog GHRP -2 (1 microg / kg / h) los yog saline rau 270 feeb thiab ntsuas lawv qhov kev noj ntawm ib qho ad libitum, noj mov buffet. Zoo ib yam li qhov tau tshaj tawm rau kev tswj hwm ghrelin, peb cov ntsiab lus tau noj 35. Thaum xam ib kg lub cev hnyav (136.0 +/- 13.0 kJ/kg [32.5 +/- 3.1 kcal/kg] vs. 101.{ {23}}/- 10.5 kJ/kg [24.2 +/- 2.5 kcal/kg], p=0.008). Cov macronutrient muaj pes tsawg leeg ntawm cov zaub mov noj tsis txawv ntawm cov xwm txheej. Raws li kev cia siab, cov ntshav hauv GH tau nce siab thaum lub sijhawm GHRP-2 infusion (AUC 5550 +/- 1090} microg/L/240 min vs. 412 +/- 161} microg/ L/240 min, p=0.003). Cov ntaub ntawv no yog thawj zaug qhia tias GHRP-2, zoo li ghrelin, nce kev noj zaub mov, qhia tias GHRP-2 yog ib qho cuab yeej tseem ceeb rau kev tshawb nrhiav ghrelin cuam tshuam rau kev noj zaub mov hauv tib neeg.