DSIP WAGGDASGE 62568-57-4 Peptide 99% Purity Lub Cev Lub Zog Lub Cev Muaj Zog

Cov ntaub ntawv ceev

Khoom Npe	DSIP
Txhais	SLEEP INDUCING PEPTIDE; WAGGDASGE; TRP-ALA-GLY-GLY-ASN-ALA-SER-GLY-GLU; TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU; TRP-ALA-GLY-GLY- ASP-ALA-SER-GLY-GLU 4H2O; DELTA SLEEP INDUCING PEPTIDE; DELTA SLEEP-INDUCING PEPTIDE 4H2O; DSIP
CAS TSIS.	62568-57-4
Cov mis qauv	C35H48N10O15
Molecular Luj	848.81
Tus Qauv Molecular
Boiling taw tes	1522.7ºC ntawm 760 mmHg
Flash point	874.7ºC
Qhov ceev	1.458 g / cm3
Dej solubility	Soluble hauv dej ntawm 0.5mg / ml
Performance index hloov	1.612
Tsos	Dawb khov-qhuav hmoov
Kev huv siab	99%
Txuj Ci Zoo	Txuj kev lag luam
Kev Mob Cia	−20°C
Ntim	2mg / vial
Lub Sij Hawm Tus Me Nyuam	3-5 Hnub Ua Haujlwm
Cov ntsiab lus them nqi	Western Union; Nyiaj Gram; Bitcoin; Litecoin; Sij Hawm Hloov Chaw Sij Hawm
Kev pab	Kev pw tsaug zog ua rau peptides thiab txhawb nqa kev pw tsaug zog

Tshawb nrhiav thiab Ntawv Siv

DSIP (Delta Pw-ua rau Peptide) yog neuropeptide pom hauv hypothalamus, pituitary, thiab qog adrenal. Nws txoj kev nyob ib leeg tau tso cai rau kev tshawb fawb ntau yam uas tau pom ntau qhov ua tau thiab thawj qhov luag haujlwm ntawm peptide no. Ua ntej, DSIP tau pom tias ua rau pw tsaug zog. Thib ob, nws yuav muaj txiaj ntsig ua kev siv tshuaj tiv thaiv kev mob mob, qee zaum ua los kho tus mob no. Thib peb, DSIP tau pom tias yuav thaiv ACTH cov kev tso tawm thiab txo qis ntawm ACTH, txhawb nqa LH tso tawm, thiab ua raws li cov tshuaj tiv thaiv ntawm cov zais somatostatin. Cov peev txheej ntawm tsim ntawm DSIP tseem tsis tau paub; Nws tuaj yeem tsim nyob hauv nruab nrab cov hlab lossis hauv cov khoom nruab nrog cev.

Raws li tau hais, DSIP tau qhia cov txiaj ntsig zoo hauv kev tsim lub zog qeeb-EEG (pw tsaug zog). Nws tau pom tias yuav pab kho cov kab mob narcolepsy thiab rov ua kom lub txaj tsis sib haum xeeb ua rau cov kev pw tsaug zog zoo ibyam. Ntau lub tebchaw tau npaj siab ua lub sijhawm pw tsaug zog, tab sis tsuas yog ob ntawm cov neeg pw-peptides tau ua kom huv rau homogeneity thiab yam ntxwv, kom deb li deb. Ib ntawm lawv, DSIP, tau pom tias yog qhov tsis muaj qhov tso tawm ntawm MW 849 thiab ua rau ntxias ntau-pw hauv luav, nas, nas, thiab tib neeg, hos hauv cov miv, qhov cuam tshuam ntawm REM pw tsaug zog muaj tseeb dua.

U-shaped ua nkhaus txiav txim tau txiav txim siab rau lub koob tshuaj ntxiv rau lub sijhawm ntawm txoj kev lis ntshav. DSIP zoo li cov khoom siv tau pom los ntawm RIA thiab immunohistochemistry hauv hlwb thiab los ntawm RIA hauv cov khoom nruab nrog nas ntawm cov nas nrog rau cov ntshav ntawm ob peb hom tsiaj. Ntxiv rau kev pw tsaug zog, peptide tseem tau pom tias cuam tshuam rau kev ua haujlwm electrophysiological, qib neurotransmitter hauv lub paj hlwb, ncig circadian thiab locomotor cov qauv, qib tshuaj hormones, kev puas siab puas ntsws, thiab kev ua si ntawm cov tshuaj neuropharmacological nrog rau lawv tshem tawm.

Kev piav qhia

Delta pw-tsim peptide, luv luv DSIP, yog neuropeptide uas thaum nkag mus rau hauv lub mesodiencephalic ventricle ntawm tus txais luav induces ntxaiv thiab raws EEG kev ua si thiab txo kev ua si lub cev muaj zog.

Delta pw-ntxias peptide tau pom thawj zaug xyoo 1974 los ntawm pab pawg Swiss Schoenenberger-Monnier uas cais nws los ntawm cov kab mob hlwb ntawm cov hlab ntshav ntawm luav hauv ib qho kev ntxias. Nws yog thawj ntseeg tias tau koom nrog hauv kev cai pw tsaug zog vim nws qhov pom meej muaj peev xwm los ntxias qeeb-nthwv pw hauv luav, tab sis kev tshawb fawb ntawm cov ncauj lus tau ua tsis haum.

DSIP yog amphiphilic peptide ntawm molecular phaus 850 daltons nrog cov amino acid motif.Nws tau pom nyob rau hauv ob qho tib si dawb thiab khi cov ntaub ntawv hauv hypothalamus, limbic system thiab pituitary li zoo li ntau yam khoom nruab nrog cev, cov nqaij thiab lub cev. Hauv cov kev ua kom sib xyaw ua ke nws muaj kev thaj yeeb nrog ntau yam peptide thiab tsis muaj peptide mediators xws li corticotropin-zoo li nruab nrab peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) thiab melanin concentrating. lawm (MCH). Nws yog ntau nyob rau hauv lub plab secretory hlwb thiab nyob rau hauv lub pancreas qhov twg nws co-localises nrog glucagon.

Kev pab

DSIP (Delta Pw-ua rau Peptide) yog neuropeptide pom hauv hypothalamus, pituitary, thiab qog adrenal. Nws txoj kev nyob ib leeg tau tso cai rau kev tshawb fawb ntau yam uas tau pom ntau qhov ua tau thiab thawj qhov luag haujlwm ntawm peptide no. Ua ntej, DSIP tau pom tias ua rau pw tsaug zog. Thib ob, nws yuav muaj txiaj ntsig ua kev siv tshuaj tiv thaiv kev mob mob, qee zaum ua los kho tus mob no. Thib peb, DSIP tau pom tias yuav thaiv ACTH cov kev tso tawm thiab txo qis ntawm ACTH, txhawb nqa LH tso tawm, thiab ua raws li cov tshuaj tiv thaiv ntawm cov zais somatostatin. Cov peev txheej ntawm tsim ntawm DSIP tseem tsis tau paub; Nws tuaj yeem tsim nyob hauv nruab nrab cov hlab lossis hauv cov khoom nruab nrog cev. Nws yog xav kom dhau los ntawm cov ntshav-hlwb teeb meem (BBB) ​​ntau yooj yim dua li cov neuropeptides feem ntau paub. Raws li tau hais, DSIP tau qhia cov txiaj ntsig zoo hauv kev tsim lub zog qeeb-EEG (pw tsaug zog). Nws tau pom tias yuav pab kho cov kab mob narcolepsy thiab rov ua kom tsaug zog uas tsis zoo rau lub cev ua kom muaj kev tsaug zog zoo.

Muaj nuj nqi

Cov cwj pwm hauv cov kev cai endocrine
Txo qis qib corticotropin qib thiab txwv nws tso tawm
Tsim kho kev tso tawm ntawm luteinizing hormone (LH)
Stimulates tso somatoliberin thiab somatotrophin zais pa thiab inhibits somatostatin zais cia.
Cov cwj pwm hauv cov txheej txheem physiological
Muaj peev xwm ua tau raws li kev cuam tshuam txog kev ntxhov siab