Melanotan 2
Melanotan-II (MT-II) / Cas No.: 121062-08-6
Sequence: Ac-NLE-c [ASP-His-d-PHE-ARG-TRP-LYS] -NH2 Tus Choj Choj Asp2-Lys7
Kev Nyab Xeeb (HPLC): 98.0%
Zog: Cov hmoov dawb dawb
Cov Qauv Nqaij: C50H69N15O9
Molecular Luj: 1024.18
MS: 
Kev Txhim Kho Ib Leeg (HPLC): 0.5% max
ntom: 1.43
Amino Acid Composition: ± 10% ntawm theoretical
Cov ntsiab lus peptide (N%): ≥80.0%
Cov Ntsiab Lus Dej (Karl Fischer): ≤8.0%
Cov ntsiab lus Acetate (HPIC): ≤10.0%
Kev sib hloov tshwj xeeb (20 / D): -55.0 ~ -65.0 ° (c = 1 1% HAc)
MS (ESI): Zoo sib xws
Tshuav Loj Loj: 95.0 ~ 105.0%
Melanotan 2 Cov Teb Ntawm Daim Ntawv Thov
Txhawb nqa tawv nqaij tsaus nti xim
Loss poob phaus
· Kev ua kom muaj libido
· Lub cev nqaij ntshiv
· Rau Txoj Kev Mob Erectile (ED)
Melanotan 2 Taw qhia:
Melanotan 2 (tseem hu ua Melanotan II) yog cov tshuaj synthetically ua ntau yam ntawm peptide hormone ib txwm ua hauv lub cev uas ua rau cov tawv nqaij melanogenesis, txheej txheem ua lub luag haujlwm rau pigmentation ntawm daim tawv nqaij. Qhov peptide hormone no, hu ua alpha-Melanocyte stimulating hormone lossis MSH, ua kom muaj qee yam melanocortin receptors hauv cov txheej txheem ntawm kev ua kom nws cov teebmeem. Qhov tseeb, MSH kuj tseem muaj kev cuam tshuam zoo rau lub cev lipid metabolism, qab los noj mov, thiab kev sib deev libido los ntawm cov melanocortin receptors. Raws li qhov tshwm sim, Melanotan 2 tau qhia hauv kev tshawb fawb los ua kom pom kev qab los noj mov, lipolytic, thiab libido-txhim kho cov teebmeem ntxiv rau kev txhawb nqa tawv nqaij. Melanotan 2 tau tshawb fawb ntau yam siv rau kev siv tiv thaiv kev tiv thaiv kev puas tsuaj ntawm ultraviolet hluav taws xob los ntawm tshav ntuj vim nws lub melanogenesis-txhawb cov yam ntxwv.
Tsis tas li ntawd, Melanotan 2 thiab ib qho zoo sib xws synthetically tsim variant, hu ua PT-141, tau kawm ntev ntev ua qhov muaj txiaj ntsig zoo rau kev kho mob ntawm kev sib daj sib deev; tshwj xeeb, txiv neej ua haujlwm erectile kawg.
Vim li cas Melanotan II
Rau kev tawm dag zog lub cev kom muaj kev sib tw nyob rau theem, muaj ntau lub sijhawm thiab sijhawm rau kev nthuav dav kom meej ua ntej lawv npaj txhij rau kev sib tw. Raug muscled thiab txhais tsuas yog accentuated los ntawm zoo ziab kom ua kab thiab cov ntsiab lus tau nrov tawm thiab ua rau pom tseeb rau cov neeg saib thiab cov kws txiav txim plaub. Nkag mus rau heptapeptide Melanotan II, tam sim no cov neeg tawm dag lub zog tuaj yeem tiv thaiv lawv tus kheej kom txhob raug tshav ntuj thaum ua kom cov melanin tawm. Qhov no ua rau muaj kev tsaus nti thiab ntau xim tawv nqaij. Thaum Melanotan II ntxiv rau peptide raws tu qauv kev ua yeeb yam dhau los, nws yuav ua rau muaj qib melanin, uas ua rau tawv nqaij tawv; Tsis tas li ntawd, nws yuav ua rau kom muaj rog poob thiab cov leeg ua kom tawv.
Melanotan 2 Cov Kev Tshawb Nrhiav thiab Cov Ntaub Ntawv Ntxiv
Melanotan thiab Melanotan 2 yog ob qho piv txwv ntawm peptide hormone alpha-melanocyte stimulating hormone (MS-MSH) uas nyiam ntxias cov tawv nqaij. Tsis zoo li Melanotan 1, Melanotan 2 tau pom tias muaj cov khoom ua rau aphrodisiac, cov nyhuv ntxiv ntawm kev muaj libido. Melanotan 2 yog ib qho kev hloov heptapeptide analog ntawm alpha-melanocyte stimulating hormone (a-MSH).
Qhov cuam tshuam ntawm Melanotan 2 ntawm kev noj haus thiab kev noj zaub mov ntawm lub chaw kuaj nas tseem tau tshawb nrhiav. Nws tau pom tias lub hauv paus melanocortin (MC) tau qhib lub suab ntawm melanotan 2 thaum pub thiab tawm hauv cov nas. Txoj kev kho mob 6-hnub ntawm Melanotan 2 tau qhia tias peptide ua rau lub cev hnyav thiab cov nplais adipose hauv viscera ntawm cov nas thiab ua rau lub cev txo qis ntawm lub cev muaj sia. Qhov no muaj qhov cuam tshuam hauv kev siv tshuaj rau kev kho mob kom ua tau kom txo qis los yog kom rog kom tsawg tshwj xeeb tshaj yog cov rog dhau thiab rog dhau. Tsis tas li ntawd, tib txoj kev tshawb no kuj tau ua pov thawj tias muaj kev pab txhawb nqa kev siv oxygen ntau ntxiv hauv cov tsiaj rog. Melanotan 2 kuj tseem pab txo qis qib ntshav dej-sulin thiab cov roj (cholesterol) thaum piv nrog kev tswj kev kho mob. Tsis tas li ntawd, nws tau hais tias melanotan 2 ua tau qis dua qib ntawm acetylcholine Ib qho kev qhia caboxylase thiab txawm tias tiv thaiv qhov txo qis ntawm carnitine thiab palmitoltransferase I mRNA hauv cov leeg nqaij-los ntawm cov leeg-pub mis ntawm cov leeg rog. Ntxiv mus, Melanotan 2 peptide ua tau nce cov roj catabolism hauv cov leeg nqaij thiab tseem txhim kho cov roj metabolism hauv cov roj 
Cim npe nrov: polypeptide tawv nqaij tawv tawv tan2, Tuam Tshoj, tuam ntxhab, cov chaw muag khoom, lub Hoobkas, cov nqi teev, hauv Tshuag, cov qauv dawb
