Testosterone Undecanoate Roj CAS: 5949-44-0

Kev piav qhia

Cov keeb kwm ntawm testosterone undecanoate yog qhov ntev thiab nyuaj. Cov tshuaj yog thawj zaug tsim nyob rau hauv 1930s raws li ib tug testosterone hloov kho, tab sis loj nce steroids chav kawm rau cov neeg laus nws tsis yog kom txog rau thaum lub 1960s uas nws pib siv dav nyob rau hauv kev kho mob chaw. Niaj hnub no, Testosterone undecanoate tseem feem ntau tau sau tseg rau cov txiv neej uas muaj cov qib testosterone tsawg, tab sis nws kuj tseem raug kawm raws li kev kho mob rau lwm yam mob xws li rog rog thiab mob qog noj ntshav.

Tam sim no nws yog hom tshuaj testosterone ntau tshaj plaws siv hauv cov tshuaj thiab tau pom tias muaj txiaj ntsig zoo ntawm kev kho ntau yam mob ntsig txog txiv neej kev yug me nyuam, xws li qis libido, erectile kawg, thiab cov phev tsawg. Testosterone undecanoate kuj qee zaum siv los ntawm daim ntawv lo los kho lwm yam mob xws li kev rog thiab kev ntxhov siab.

Testosterone undecanoate yog Testosterone hloov kho (TRT) uas tau pom tias pab ua kom cov leeg nqaij hauv cov txiv neej. Testosterone undecanoate yog Ameslikas tsim los ua kev kho mob rau castration-resistant prostate cancer, tab sis txij li thaum nws tau pom tias yog ib qho zoo TRT rau cov leeg nqaij nce hauv cov txiv neej. Testosterone undecanoate tuaj yeem siv ib leeg lossis ua ke nrog lwm cov tshuaj testosterone, xws li testosterone enanthate lossis cypionate.

Testosterone undecanoate yog Testosterone derivative uas tau pom los ua kom cov leeg nce hauv cov neeg siv. Cov tshuaj no yog Ameslikas tsim los ua kev kho mob rau hypogonadism, tab sis txij li thaum nws tau pom los ua ib qho kev tsim cov leeg nqaij zoo hauv nws txoj cai.

Cov ntaub ntawv kho mob

Qhov taw qhia

Testosterone undecanoate yog qhia rau testosterone hloov kho nyob rau hauv cov txiv neej laus rau tej yam kev mob txuam nrog ib tug deficiency los yog tsis muaj endogenous testosterone. Cov xwm txheej no suav nrog:

Congenital los yog kis tau tus thawj hypogonadism: testicular tsis ua hauj lwm vim cryptorchidism, ob tog torsion, orchitis, vanishing testis syndrome, orchiectomy, Klinefelter's syndrome, tshuaj kho mob, los yog tshuaj lom puas tsuaj los ntawm cawv los yog hlau hnyav. Cov txiv neej no feem ntau muaj cov tshuaj hormones testosterone tsawg thiab gonadotropins (follicle-stimulating hormone FSH, luteinizing hormone LH) saum toj no ntau yam.

Congenital lossis kis tau tus mob hypogonadotropic hypogonadism: gonadotropin lossis luteinizing hormone-releasing hormone (LHRH) deficiency lossis pituitary-hypothalamic raug mob los ntawm qog nqaij hlav, raug mob, lossis hluav taws xob. Cov txiv neej no muaj cov tshuaj testosterone tsawg tsawg tab sis muaj gonadotropins nyob rau hauv ib txwm lossis tsawg.

Testosterone undecanoate tsis siv los kho lub hnub nyoog ntsig txog hypogonadism.

Mechanism ntawm kev ua

Testosterone yog ib qho tseem ceeb ntawm txiv neej cov tshuaj hormones uas yog lub luag haujlwm rau kev loj hlob thiab kev loj hlob ntawm cov txiv neej pw hauv nruab nrog cev thiab kev saib xyuas cov yam ntxwv ntawm kev sib deev, xws li kev loj hlob thiab kev loj hlob ntawm cov txiv neej poj niam cev xeeb tub, kev loj hlob ntawm txiv neej cov plaub hau faib, suab qaum thickening. , thiab kev hloov pauv hauv lub cev musculature thiab rog faib. Txiv neej hypogonadism, uas tshwm sim los ntawm qhov tsis txaus testosterone secretion, muaj ob lub ntsiab lus tseem ceeb: thawj hypogonadism yog tshwm sim los ntawm qhov tsis xws luag hauv gonads, qhov thib ob hypogonadism yog qhov tsis ua haujlwm ntawm hypothalamus (los yog pituitary) los tsim cov gonadotropins txaus (FSH thiab LH).

Hauv kev ncig, testosterone undecanoate yog cleaved los ntawm endogenous non-specific esterases tso tawm testosterone, lub active tivthaiv ntawm lub compound. Lub undecanoate sab saw yog pharmacologically inactive. Testosterone tuaj yeem hloov pauv ntxiv los ntawm 5 reductase rau nws daim ntawv ua haujlwm lom neeg ntau dua, dihydrotestosterone (DHT). Kev ua ntawm testosterone thiab DHT yog kho los ntawm androgen receptor, uas tau nthuav dav hauv ntau cov ntaub so ntswg, nrog rau cov pob txha, cov leeg, prostate, thiab cov ntaub so ntswg adipose. Testosterone khi rau androgen receptors nrog siab affinity thiab tswj lub hom phiaj gene transcription koom nrog nyob rau hauv ib txwm kev loj hlob thiab kev loj hlob ntawm cov txiv neej cov kab mob thiab kev saib xyuas ntawm lwm yam kev sib deev cwj pwm. prostate loj, thiab hloov pauv hauv lipid profile.

Testosterone Undecanoate Ua Haujlwm?

Muaj ib lub tswv yim los tsim ib qho anabolic androgenic qhov ncauj steroid uas yuav siv tau rau cov txiv neej uas tsis tshua muaj testosterone thiab cov khoom zoo li ua tiav qhov nws yuav tsum tau ua. Txawm li cas los xij, cov khoom no tsis tau nrov heev, vim tias cov tshuaj pleev xim (xws li androgel) thiab tshwj xeeb tshaj yog cov tshuaj testosterones tau suav tias muaj txiaj ntsig ntau dua.

Cov khoom no tsis dhau mus rau hauv daim siab tsis zoo li lwm cov tshuaj steroids hauv qhov ncauj - tab sis cov khoom no mus los ntawm cov kab mob lymphatic. Qhov no yog dab tsi zam cov steroid los ntawm kev tshem tawm ntawm daim siab thiab nkag mus rau hauv cov ntshav. Qhov no yog qhov txawv ntawmTestosterone Undecanoatethiab lwm qhov ncauj steroids uas yog methylated lossis 17AA.

Thaum nws nkag mus rau hauv cov ntshav - cov khoom lag luam ua haujlwm zoo ib yam li lwm yam testosterone. Qee cov txiaj ntsig ntawm kev txhawb nqa qib testosterone muaj xws li: pw tsaug zog zoo dua thiab txhawb libido. Cov khoom no yog kev zoo siab thiab kev ntseeg siab rau cov txiv neej tab sis qhov tseem ceeb tshaj plaws - nws pab koj kom poob rog thiab nce cov leeg.

Testosterone Undecanoate siv rau dab tsi?

Testosteroneyog thawj txiv neej cov tshuaj hormones thiab yog lub luag haujlwm rau ntau tus txiv neej zoo li cov yam ntxwv xws li poob rog, cov leeg thiab lub zog nce, lub ntsej muag plaub hau loj hlob thiab lwm yam.

Nyob rau hauv cov chaw kho mob, cov khoom yog muab rau cov neeg uas raug kev txom nyem los ntawm tsawg testosterone ntau lawm tab sis rau bodybuilders, nws yog muab raws li ib tug kev ua tau zoo tshuaj. Tab sis cov khoom tsis yog siv dav heev vim nws suav tias tsis muaj zog.

Txawm li cas los xij, cov khoom lag luam yuav muaj txiaj ntsig zoo rau kev ua haujlwm, ntawm libido thiab rov qab los, tab sis tsuas yog thaum cov khoom no siv ntau dua. Cov xov xwm zoo yog tias cov khoom no tuaj yeem siv los kho cov testosterone qis lossis ua cov khoom lag luam txhim kho yam tsis muaj kev puas tsuaj rau koj lub siab.

Testosterone Undecanoatefeem ntau yog siv los ntawm bodybuilders uas tsis xav txhaj cov khoom txawm yog vim li cas los yog siv cov tshuaj pleev ib ce vim yog vim li cas (feem ntau lawv muaj xws li qhov chaw txhaj tshuaj, ua xua rau tshuaj pleev ib ce los yog lwm yam).

Txawm hais tias daim ntawv no ntawm testosterone yog siv los ua ib tugPED (kev ua tau zoo dua tshuaj)- nws tsis pom zoo kom siv cov khoom testosterone undecanoate ib leeg vim tias cov khoom tsis muaj zog heev kom pom cov txiaj ntsig. Cov khoom yuav ua haujlwm zoo thaum sib xyaw ua ke kom zoo dua rau pawg.

Testosterone Undecanoate Side Effects

Nws tau hais ua ntej qhov tseeb tias testosterone undecanoate (Andriol lossis lwm yam khoom) yog ib yam khoom uas tsis muaj zog heev piv rau lwm cov tshuaj testosterone. Qhov no txhais tau hais tias cov kev mob tshwm sim profile tsawg heev nrog cov khoom no ib yam nkaus.

Txawm li cas los xij, cov kev mob tshwm sim zoo nkauj npaum li cas nrog rau lwm yam khoom siv testosterone vim tias thaum kawg - koj tau txais testosterone. Qhov no txhais tau hais tias cov kev mob tshwm sim estrogenic tuaj yeem ua tau (aromatization), androgenic phiv tau, cov kev mob plawv thiab cov tshuaj tiv thaiv testosterone.
Tag nrho cov kev mob tshwm sim no tsis zoo li tshwm sim, yog nyob ntawm koob tshuaj thiab lawv tuaj yeem tswj tau yooj yim (los ntawm kev txo cov tshuaj lossis los ntawm kev ntxiv lub teeb tshuaj tiv thaiv estrogen rau kev cuam tshuam nrog estrogenic phiv).

Peb Qhov Zoo

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